MY VERDICT Reuters claim is false. The challenged claim is correct. The earliest available COVID-19 vaccines will indeed genetically modify humans, whether using foreign genes to alter the host’s gene expression or altering the host’s DNA to perform the same function. DNA vaccines do indeed integrate foreign DNA into the cell nucleus of its recipient. Injecting into the tissues is only the first stage, the DNA/RNA must make its way into the host cell’s nucleus before it can stimulate the required immune response. In addition to false claims, Reuters use of pedantic semantics has also confused the issue.